You may have read a posting dis-recommending PSU1 and PSU2 for Oracle Multitenant 22.214.171.124 especially in RAC/GI environments earlier this week. Actually following a lot of internal discussions I will post some advice and clarification later this week.
Now I have an useful update:
Datapatch Issues are covered within a separate MOS Note making it easier to keep track and find workarounds for known issues.
Please see MOS Note:1609718.1 Datapatch Known Issues